health info
September 08, 2019
Factors That Make Lymph Nodes Cancer Cells Spread to Other Organs
Lymph node cancer or lymphoma suffered by a person can be increasingly spread to other body organs.
Cancer that spreads or is known as metastasis occurs at stage 4, in which cancer cells begin to spread to parts of the body that are far outside the lymphatic system, such as the spinal cord, lungs, and liver.
Lymphoma is a cancer that comes from a type of white blood cell, called a lymphocyte. These cells travel through the lymphatic system which is part of the immune system. The spread of cancer cells to other parts of the body can contribute about 90 percent of cancer deaths.
From a journal entitled Tumor metastasis to lymph nodes requires YAP-dependent metabolic adaptation published by Science on February 8, 2019, cancer cells that grow in lymph nodes can easily reach other organs. This condition can worsen patient survival.
Oncologist Choong-kun Lee and the team at Basic Science (IBS) and Korea Advanced Institute of Science and Technology (KAIST) in Daejeon, South Korea examined the growth and spread of lymph node cancer cells.
Lymph node cancer cells that spread can increase the gene linked to fatty acids that are broken down to produce energy (known as fatty acid oxidation). Researchers also found that, unlike other organs, lymph is rich in various fatty acids.
"This unexpected result gives me strong confidence that metastatic lymph node tumor cells prefer to use fatty acids as energy,"
Fatty Acids and Bile
Spread of lymph nodes is also influenced by fatty acids and bile. Researchers reveal, the type of bile acid that is known only to be detected in the liver and intestinal tract is surprisingly found in metastatic lymph nodes.
"It's very interesting that bile acids accumulate in the metastatic lymph nodes, but bile acids are absent in healthy lymph nodes. Initial analysis shows, metastatic lymph node cancer itself can produce bile acids. Bile acids can stimulate further growth of the healthy lymph nodes. lymph node tumors that spread, "Lee added.
Lymph nodes are small parts of the body that contain immune cells to fight harmful substances, such as cancer cells. Despite the underlying immune mechanism, cancer cells can adapt and grow in lymph nodes.
Metastatic lymph nodes are very important in cancer staging, treatment, and treatment.
Symptoms of lymphoma stage 4
According to cancer researcher Christina Chun, symptoms of stage 4 lymphoma can include:
The presence of symptoms is getting worse which is marked by the condition of unintentional loss of more than 10 percent of body weight in 6 months, fever that comes and goes without infection, and sweat soaking wet at night.
Cancer that spreads or is known as metastasis occurs at stage 4, in which cancer cells begin to spread to parts of the body that are far outside the lymphatic system, such as the spinal cord, lungs, and liver.
Lymphoma is a cancer that comes from a type of white blood cell, called a lymphocyte. These cells travel through the lymphatic system which is part of the immune system. The spread of cancer cells to other parts of the body can contribute about 90 percent of cancer deaths.
From a journal entitled Tumor metastasis to lymph nodes requires YAP-dependent metabolic adaptation published by Science on February 8, 2019, cancer cells that grow in lymph nodes can easily reach other organs. This condition can worsen patient survival.
Oncologist Choong-kun Lee and the team at Basic Science (IBS) and Korea Advanced Institute of Science and Technology (KAIST) in Daejeon, South Korea examined the growth and spread of lymph node cancer cells.
Lymph node cancer cells that spread can increase the gene linked to fatty acids that are broken down to produce energy (known as fatty acid oxidation). Researchers also found that, unlike other organs, lymph is rich in various fatty acids.
"This unexpected result gives me strong confidence that metastatic lymph node tumor cells prefer to use fatty acids as energy,"
Fatty Acids and Bile
Spread of lymph nodes is also influenced by fatty acids and bile. Researchers reveal, the type of bile acid that is known only to be detected in the liver and intestinal tract is surprisingly found in metastatic lymph nodes.
"It's very interesting that bile acids accumulate in the metastatic lymph nodes, but bile acids are absent in healthy lymph nodes. Initial analysis shows, metastatic lymph node cancer itself can produce bile acids. Bile acids can stimulate further growth of the healthy lymph nodes. lymph node tumors that spread, "Lee added.
Lymph nodes are small parts of the body that contain immune cells to fight harmful substances, such as cancer cells. Despite the underlying immune mechanism, cancer cells can adapt and grow in lymph nodes.
Metastatic lymph nodes are very important in cancer staging, treatment, and treatment.
Symptoms of lymphoma stage 4
According to cancer researcher Christina Chun, symptoms of stage 4 lymphoma can include:
enlarged lymph nodes under the skin
exhausted hot coldloss of appetitecontinuous itching coughhard to breathechest painbloatedeasy bruising or bleedingfrequent infectionsnausea or vomiting
The presence of symptoms is getting worse which is marked by the condition of unintentional loss of more than 10 percent of body weight in 6 months, fever that comes and goes without infection, and sweat soaking wet at night.