Speaker: Tsinghua University, Beijing Tsinghua Chang Gung Memorial Hospital, Severe and Critical Principal Physician Feng Lili
Hyperlipidemia is a major enemy of health. Especially after entering middle-aged and old age, it often induces atherosclerosis. It is also a healthy killer of many organs, especially severe hypertriglyceridemia, which may also cause acute pancreatitis.
In recent years, with the improvement of people's living standards, acute pancreatitis caused by hypertriglyceridemia is on the rise, accounting for about 14%, and up to 56% during pregnancy. Many people with high triglycerides have obesity problems. Once they are overeating, food is too greasy, or extremely tired, they often cause abdominal pain, but they often mistakenly believe that they have “stomach disease” and “not eating properly”. Diagnosis and treatment delays can sometimes even be fatal.
There are three main pathogenesis of acute pancreatitis caused by hyperlipidemia: (1) increased blood viscosity leads to pancreatic microcirculatory disorder and pancreatic tissue hypoxia; (2) fat embolism from outside the pancreas, such as accumulation of serum lipid particles, Blocking the blood vessels of the pancreas; (3) There are a lot of lipase in the capillaries and interstitial cells of the pancreas. In the case of elevated triglycerides in the blood, lipase can act on triglycerides and release toxic free fatty acids. It has a toxic effect on the pancreas.
In addition to fasting, rehydration, inhibition of pancreatic secretion, etc., the treatment of acute pancreatitis caused by hypertriglyceridemia should reduce blood lipid levels as soon as possible, and can be treated with plasma exchange and insulin.
In addition, pancreatitis has a 20% chance of recurrence, and most patients with hyperlipidemia do not have strict lipid control, and the disease is prone to recurrent episodes, eventually developing into complications such as chronic pancreatitis and diabetes. Therefore, after the patient is cured, it should also pay attention to: 1. Adjust the diet structure, reasonable diet; 2. Strengthen exercise, control weight; 3. Regular life, quit smoking and alcohol; 4. Regular monitoring of blood lipids, through oral Bet or statins Serum triglycerides were reduced to 2.2 moles per liter.
Finally, everyone is reminded that if you have hyperlipidemia, fatty liver or obesity, if you have persistent severe abdominal pain, don't care. If you think about the possibility of pancreatitis, go to the hospital immediately, so as not to miss the best time.
No comments:
Post a Comment